Proto-Oncogene Proteins c-kit

"Proto-Oncogene Proteins c-kit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEINS C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis.

Descriptor ID	D019009
MeSH Number(s)	D08.811.913.696.620.682.725.400.050 D12.776.543.750.630.124 D12.776.543.750.705.852.150.100 D12.776.543.750.750.400.200.170 D12.776.624.664.700.183
Concept/Terms	Proto-Oncogene Proteins c-kit Proto-Oncogene Proteins c-kit Proto Oncogene Proteins c kit c-kit, Proto-Oncogene Proteins Stem Cell Factor Receptor SCF Receptor p145 c-kit c-kit, p145 p145 c kit p145(c-kit) p145c-kit p145c kit CD117 Antigen Antigens, CD117 CD117 Antigens Proto-Oncogene Protein c-kit Proto Oncogene Protein c kit c-kit, Proto-Oncogene Protein c-kit Protein c kit Protein kit Proto-Oncogene Protein Proto-Oncogene Protein, kit kit Proto Oncogene Protein Receptor, Stem Cell Factor Proto-Oncogene Protein kit Proto Oncogene Protein kit c-kit Receptor c kit Receptor

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-kit".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
Proto-Oncogene Proteins c-kit [D08.811.913.696.620.682.725.400.050]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptor Protein-Tyrosine Kinases [D12.776.543.750.630]
Proto-Oncogene Proteins c-kit [D12.776.543.750.630.124]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Colony-Stimulating Factor [D12.776.543.750.705.852.150]
Proto-Oncogene Proteins c-kit [D12.776.543.750.705.852.150.100]
Receptors, Peptide [D12.776.543.750.750]
Receptors, Growth Factor [D12.776.543.750.750.400]
Receptors, Colony-Stimulating Factor [D12.776.543.750.750.400.200]
Proto-Oncogene Proteins c-kit [D12.776.543.750.750.400.200.170]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Proto-Oncogene Proteins c-kit [D12.776.624.664.700.183]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogene Proteins c-kit".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-kit".

publications

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