Signaling Lymphocytic Activation Molecule Family Member 1
"Signaling Lymphocytic Activation Molecule Family Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.
| Descriptor ID |
D000071177
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| MeSH Number(s) |
D12.776.395.550.736.500 D12.776.543.550.746.500 D12.776.543.750.705.970.500
|
| Concept/Terms |
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