Promyelocytic Leukemia Protein

"Promyelocytic Leukemia Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A tripartite motif protein that contains three ZINC FINGERS, including a RING FINGER DOMAIN, at its N-terminal. Several nuclear and one cytoplasmic isoforms result from alternative splicing of the PML gene; most nuclear isoforms localize to subnuclear structures (PML nuclear bodies) that are disrupted in ACUTE PROMYELOCYTIC LEUKEMIA cells.

Descriptor ID	D000071156
MeSH Number(s)	D12.776.624.776.654 D12.776.660.745 D12.776.930.713 D12.776.934.500
Concept/Terms	Promyelocytic Leukemia Protein Promyelocytic Leukemia Protein RNF71 Protein TRIM19 Protein

Below are MeSH descriptors whose meaning is more general than "Promyelocytic Leukemia Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Neoplasm Proteins [D12.776.624]
Tumor Suppressor Proteins [D12.776.624.776]
Promyelocytic Leukemia Protein [D12.776.624.776.654]
Nuclear Proteins [D12.776.660]
Promyelocytic Leukemia Protein [D12.776.660.745]
Transcription Factors [D12.776.930]
Promyelocytic Leukemia Protein [D12.776.930.713]
Tripartite Motif Proteins [D12.776.934]
Promyelocytic Leukemia Protein [D12.776.934.500]

Below are MeSH descriptors whose meaning is related to "Promyelocytic Leukemia Protein".

Below are MeSH descriptors whose meaning is more specific than "Promyelocytic Leukemia Protein".

publications

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